NUMBL anticorps (AA 336-537)

N° du produit ABIN7601366

Cet anticorps anti-NUMBL est un anticorps Lapin Polyclonal détectant NUMBL dans WB, ELISA et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NUMBL anticorps (AA 336-537) (ABIN7601366)

Antigène: NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUMBL est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-NUMBL anticorps

Épitope: AA 336-537

Fonction: Anti-NUMBL Antibody Picoband®

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Anti-NUMBL Antibody Picoband® (ABIN7601366). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NUMBL recombinant protein (Position: R336-A537). Human NUMBL shares 91.1% and 89.4% amino acid (aa) sequence identity with mouse and rat NUMBL, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Huang, E. J., Li, H., Tang, A. A., Wiggins, A. K., Neve, R. L., Zhong, W., Jan, L. Y., Jan, Y. N. Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev. 19: 138-151, 2005. 2. Li, H.-S., Wang, D., Shen, Q., Schonemann, M. D., Gorski, J. A., Jones, K. R., Temple, S., Jan, L. Y., Jan, Y. N. Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron 40: 1105-1118, 2003. 3. Margolis, R. L., Abraham, M. R., Gatchell, S. B., Li, S.-H., Kidwai, A. S., Breschel, T. S., Stine, O. C., Callahan, C., McInnis, M. G., Ross, C. A. cDNAs with long CAG trinucleotide repeats from human brain. Hum. Genet. 100: 114-122, 1997.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur NUMBL

Antigène: NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))

Autre désignation: NUMBL

Sujet:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: Numb-like protein is a protein that in humans is encoded by the NUMBL gene. NUMBL [numb (drosophila) homolog-like] is functionally related to NUMB, a protein that plays an essential role in the determination of cell fate for sensory organ and neural development. Polyglutamine repeats in the NUMBL gene have been associated with schizophrenia in two unrelated populations. Alternate names for NUMBL include NBL, CAG3A, CTG3a, NUMBR, TNRC23, and NUMBLIKE.

Poids moléculaire: 72 kDa

ID gène: 9253

UniProt: Q9Y6R0

Pathways: Cell-Cell Junction Organization